All Researches

Explore our comprehensive database of peer-reviewed clinical studies and scientific literature supporting the active ingredients in Daily Shield.

Improves muscle glycogen storage overcompensation and limits fatigue caused by excessive physical training.- Cheng et al. (2025)

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Facilitates rapid fatigue recovery by activating the metabolic AMPK and AKT/mTOR signaling pathways.- Song et al. (2015)

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Reviews structural anti-fatigue properties of C. militaris-derived polysaccharides that help maintain prolonged glycogen status.- Miao et al. (2022)

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Outlines how the structural resemblance of C. militaris nucleosides to adenosine helps actively accelerate mitochondrial ATP resynthesis.- Jędrejko K.J. et al. (2021)

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Elevates peripheral blood oxygen saturation ($SpO_2$) and extends treadmill running time to exhaustion.- Pasha et al. (2024)

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Enhances maximal oxygen transport, shifts ventilatory thresholds rightward, and accelerates post-exercise biological recovery in humans.- Jędrejko M. et al. (2026)

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Protects the erythrocyte system and prevents sports-induced runner's anemia during high-volume training phases.- Nakamura et al. (2024)

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Improves submaximal endurance kinetics, immune resistance, and athletic hematological profiles.- Shu et al. (2025)

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Modulates acute exercise-induced oxidative stress to sustain high cardiorespiratory power output.- Clemente-Suárez et al. (2023)

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Protects vascular endothelia and lung tissue against chronic inflammatory damage caused by particulate matter air pollutants (PM2.5).- Park (2025)

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Stimulates the structural development of the testes and increases sperm concentration/motility in juvenile models.- Jin et al. (2022)

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Directly elevates serum testosterone levels, sperm count, and motility in healthy subjects.- Chang et al. (2008)

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Resolves subfertility by significantly boosting normal sperm morphology, progressive motility, and overall viability.- Lin et al. (2007)

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Preserves testicles from bisphenol A toxicity and restores testosterone synthesis via upregulating StAR, CYP11A1, and 3β-HSD.- Wang et al. (2016)

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Mitigates the age-related decline of testicular endocrine function under long-term cordycepin administration.- Sohn et al. (2012)

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Suppresses diabetic nephropathy-induced renal fibrosis and collagen deposition by upregulating tubular autophagy.- Chen D.D. et al. (2019a)

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Attenuates diabetic nephropathy and insulin resistance when C. militaris is grown on a ginkgo seed substrate.- Lin S.Z. et al. (2025)

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Identifies the genomic pathway and enzymatic cascade regulating high-yield cordycepin biosynthesis in laboratory strains.- Wu X. et al. (2021)

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Prevents light-evoked visual function deterioration and retinal ganglion cell loss in mice using carotenoid-rich extracts.- Chen B.Y. et al. (2022)

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Assesses the safe immunomodulatory response of a standardized C. militaris beverage in healthy adults.- Ontawong et al. (2024)

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Promotes physiological bone mineral density and tooth structure maintenance via cordycepin extract.- Jędrejko K. et al. (2022)

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Identifies dietary properties, preparation safety, and nutritional constituents of artificially cultured fruiting bodies.- Jędrejko K. et al. (2022)

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Optimizes solid-state fermentation yields to ameliorate chronic oxidative stress and support liver parenchyma health.- Cho et al. (2025)

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Stimulates tumoricidal M1 macrophage polarization and tumor-clearing immune cytokines.- Chen L. et al. (2024)

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Provides therapeutic tumor-suppressing, anti-proliferative, and metabolic pathway interventions via cordycepin.- Zhang et al. (2024)

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Inhibits cancer cell lines and reduces metastatic progression in preclinical models.- Yu G. et al. (2024)

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Study protocol testing whether Cordyceps militaris capsules slow lung function (FEV1) decline in COPD patients over 24 weeks.- Lin S. et al. (2026)

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Cordyceps-based nanoemulsion shows measurable antioxidant, antimicrobial, and anti-inflammatory activity relevant to airway defense.- Rupa E.J. et al. (2020)

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Identifies chemical "quality markers" in Cordyceps militaris responsible for improving respiratory disease outcomes.- Author not listed in indexed abstract (2025) — PubMed ID 42543281

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First evidence that Cordyceps militaris compounds regulate ion transport in human airway epithelial (Calu-3) cells.- Author not listed in indexed abstract (2008) — ScienceDirect

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ARA301 extract suppresses mucus buildup and inflammation in a bacterial lung-injury mouse model.- Seong H.K. et al. (2025)

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COVID-19 patients on Cordyceps adjuvant therapy recovered faster from dyspnoea and low blood-oxygen symptoms.- Author not listed in indexed abstract (2023) — PMC10505833

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Athletes on Cordyceps militaris infusion sustained 95% blood-oxygen saturation through a 5-min treadmill test, vs. under 70% in controls.- Pasha S.M. et al. (2024)

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3 weeks of a Cordyceps militaris blend significantly raised VO2max (+4.8 ml/kg/min) and time-to-exhaustion (+69.8 sec) in healthy adults.- Hirsch K.R. et al. (2016/2017)

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Cordyceps militaris extract activates the ATP-generation pathway in mice, improving exercise capacity independent of fatigue markers.- Choi E., Oh J., Sung G.H. (2020)

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Genomic/transcriptome mapping shows cordycepin synthesis is directly wired into core cellular energy metabolism.- Author not listed in indexed abstract (2024) — PMC11120935

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Metabolic network analysis confirms cordycepin production is coupled to adenosine (energy-currency) metabolism.- Author not listed in indexed abstract (2018) — PMC6006141

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Combined with arginine/citrulline, Cordyceps militaris improved endurance performance in hot-weather runners via ATP/endothelial pathways.- Author not listed in indexed abstract (2016) — ResearchGate

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Cordyceps militaris fruit-body extract reduced testosterone breakdown and testosterone-driven prostate enlargement in a male-andropause rat model.- Kusama K. et al. (2020)

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Improved mating behavior, erectile function, and testicular function in diabetic male rats with low testosterone.- Pohsa et al. (2020)

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8-week RCT beverage in healthy adults significantly raised natural-killer (NK) immune cell activity and lowered inflammatory cytokines.- Ontawong A. et al. (2024)

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Ethyl acetate fraction showed strong uric-acid-lowering (anti-gout) activity plus antioxidant and antibacterial effects.- Author not listed in indexed abstract (2019) — PubMed 30699961

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Adjunct to duloxetine significantly improved sleep quality in depression patients with insomnia over 6 weeks.- Zhou J. et al. (2021)

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Reduces oxidative stress and boosts immune T-cell activity to inhibit metastatic melanoma spread in vitro.- Author not listed in indexed abstract (2022) — PMC9404731

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Regulates lipid metabolism and reduces menopause-related obesity markers in an ovariectomized rat model.- Author not listed in indexed abstract (2022) — PMC9102749

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Byproduct (spent substrate) extract shows antimicrobial, antioxidant, and dandruff-yeast-inhibiting activity.- Zhang D. et al. (2023)

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All Researches

Improves muscle glycogen storage overcompensation and limits fatigue caused by excessive physical training.- Cheng et al. (2025)

Facilitates rapid fatigue recovery by activating the metabolic AMPK and AKT/mTOR signaling pathways.- Song et al. (2015)

Reviews structural anti-fatigue properties of C. militaris-derived polysaccharides that help maintain prolonged glycogen status.- Miao et al. (2022)

Outlines how the structural resemblance of C. militaris nucleosides to adenosine helps actively accelerate mitochondrial ATP resynthesis.- Jędrejko K.J. et al. (2021)

Elevates peripheral blood oxygen saturation ($SpO_2$) and extends treadmill running time to exhaustion.- Pasha et al. (2024)

Enhances maximal oxygen transport, shifts ventilatory thresholds rightward, and accelerates post-exercise biological recovery in humans.- Jędrejko M. et al. (2026)

Protects the erythrocyte system and prevents sports-induced runner's anemia during high-volume training phases.- Nakamura et al. (2024)

Improves submaximal endurance kinetics, immune resistance, and athletic hematological profiles.- Shu et al. (2025)

Modulates acute exercise-induced oxidative stress to sustain high cardiorespiratory power output.- Clemente-Suárez et al. (2023)

Protects vascular endothelia and lung tissue against chronic inflammatory damage caused by particulate matter air pollutants (PM2.5).- Park (2025)

Stimulates the structural development of the testes and increases sperm concentration/motility in juvenile models.- Jin et al. (2022)

Directly elevates serum testosterone levels, sperm count, and motility in healthy subjects.- Chang et al. (2008)

Resolves subfertility by significantly boosting normal sperm morphology, progressive motility, and overall viability.- Lin et al. (2007)

Preserves testicles from bisphenol A toxicity and restores testosterone synthesis via upregulating StAR, CYP11A1, and 3β-HSD.- Wang et al. (2016)

Mitigates the age-related decline of testicular endocrine function under long-term cordycepin administration.- Sohn et al. (2012)

Suppresses diabetic nephropathy-induced renal fibrosis and collagen deposition by upregulating tubular autophagy.- Chen D.D. et al. (2019a)

Attenuates diabetic nephropathy and insulin resistance when C. militaris is grown on a ginkgo seed substrate.- Lin S.Z. et al. (2025)

Identifies the genomic pathway and enzymatic cascade regulating high-yield cordycepin biosynthesis in laboratory strains.- Wu X. et al. (2021)

Prevents light-evoked visual function deterioration and retinal ganglion cell loss in mice using carotenoid-rich extracts.- Chen B.Y. et al. (2022)

Assesses the safe immunomodulatory response of a standardized C. militaris beverage in healthy adults.- Ontawong et al. (2024)

Promotes physiological bone mineral density and tooth structure maintenance via cordycepin extract.- Jędrejko K. et al. (2022)

Identifies dietary properties, preparation safety, and nutritional constituents of artificially cultured fruiting bodies.- Jędrejko K. et al. (2022)

Optimizes solid-state fermentation yields to ameliorate chronic oxidative stress and support liver parenchyma health.- Cho et al. (2025)

Stimulates tumoricidal M1 macrophage polarization and tumor-clearing immune cytokines.- Chen L. et al. (2024)

Provides therapeutic tumor-suppressing, anti-proliferative, and metabolic pathway interventions via cordycepin.- Zhang et al. (2024)

Inhibits cancer cell lines and reduces metastatic progression in preclinical models.- Yu G. et al. (2024)

Study protocol testing whether Cordyceps militaris capsules slow lung function (FEV1) decline in COPD patients over 24 weeks.- Lin S. et al. (2026)

Cordyceps-based nanoemulsion shows measurable antioxidant, antimicrobial, and anti-inflammatory activity relevant to airway defense.- Rupa E.J. et al. (2020)

Identifies chemical "quality markers" in Cordyceps militaris responsible for improving respiratory disease outcomes.- Author not listed in indexed abstract (2025) — PubMed ID 42543281

First evidence that Cordyceps militaris compounds regulate ion transport in human airway epithelial (Calu-3) cells.- Author not listed in indexed abstract (2008) — ScienceDirect

ARA301 extract suppresses mucus buildup and inflammation in a bacterial lung-injury mouse model.- Seong H.K. et al. (2025)

COVID-19 patients on Cordyceps adjuvant therapy recovered faster from dyspnoea and low blood-oxygen symptoms.- Author not listed in indexed abstract (2023) — PMC10505833

Athletes on Cordyceps militaris infusion sustained 95% blood-oxygen saturation through a 5-min treadmill test, vs. under 70% in controls.- Pasha S.M. et al. (2024)

3 weeks of a Cordyceps militaris blend significantly raised VO2max (+4.8 ml/kg/min) and time-to-exhaustion (+69.8 sec) in healthy adults.- Hirsch K.R. et al. (2016/2017)

Cordyceps militaris extract activates the ATP-generation pathway in mice, improving exercise capacity independent of fatigue markers.- Choi E., Oh J., Sung G.H. (2020)

Genomic/transcriptome mapping shows cordycepin synthesis is directly wired into core cellular energy metabolism.- Author not listed in indexed abstract (2024) — PMC11120935

Metabolic network analysis confirms cordycepin production is coupled to adenosine (energy-currency) metabolism.- Author not listed in indexed abstract (2018) — PMC6006141

Combined with arginine/citrulline, Cordyceps militaris improved endurance performance in hot-weather runners via ATP/endothelial pathways.- Author not listed in indexed abstract (2016) — ResearchGate

Cordyceps militaris fruit-body extract reduced testosterone breakdown and testosterone-driven prostate enlargement in a male-andropause rat model.- Kusama K. et al. (2020)

Improved mating behavior, erectile function, and testicular function in diabetic male rats with low testosterone.- Pohsa et al. (2020)

8-week RCT beverage in healthy adults significantly raised natural-killer (NK) immune cell activity and lowered inflammatory cytokines.- Ontawong A. et al. (2024)

Ethyl acetate fraction showed strong uric-acid-lowering (anti-gout) activity plus antioxidant and antibacterial effects.- Author not listed in indexed abstract (2019) — PubMed 30699961

Adjunct to duloxetine significantly improved sleep quality in depression patients with insomnia over 6 weeks.- Zhou J. et al. (2021)

Reduces oxidative stress and boosts immune T-cell activity to inhibit metastatic melanoma spread in vitro.- Author not listed in indexed abstract (2022) — PMC9404731

Regulates lipid metabolism and reduces menopause-related obesity markers in an ovariectomized rat model.- Author not listed in indexed abstract (2022) — PMC9102749

Byproduct (spent substrate) extract shows antimicrobial, antioxidant, and dandruff-yeast-inhibiting activity.- Zhang D. et al. (2023)